Thomas J. Sugrue's The Origins of the Urban Crisis: Race and Inequality in Postwar Detroit (1997) is a great book -- and in some ways a simple one. It provides extensive, fine-grained documentation of two or three (depending on how you count) relentless forces that destroyed Detroit.
The first was the hemorrhaging of manufacturing jobs that was in full flow by the early fifties, and could only have been stemmed by national industrial policies unthinkable in the United States: a rollback of Taft-Hartley's enablement of state right-to-work laws; a German-style role for labor in corporate management; legal restrictions on companies' right to lay off workers or move manufacturing operations as they saw fit.
The second was the vicious, rooted, legally codified and government-sanctioned racism that kept African Americans at the bottom of the labor totem pole, consigning them to the hardiest, dirtiest, poorest-paying and least secure factory jobs and excluding them skilled crafts, retail service and a host of other occupations.